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IP Roundup: Life Technologies, Theranos, Bioinfra

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Life Technologies of Carlsbad, Calif., has received US Patent No. 8,435,395, "Methods and apparatus for measuring analytes using large scale FET arrays." Methods are claimed for producing large-scale, filed-effect-transistor arrays using conventional complementary metal–oxide–semiconductor processing techniques. According to the inventors, such arrays may be employed to detect a presence or concentration changes of various analyte types in a variety of chemical and biological processes.


Bioinfra of Seoul, South Korea, has received US Patent No. 8,435,748, "Method for monitoring, diagnosing, and screening cancer through measuring the concentration of des-R prothrombin activation peptide fragment F2 (des-R F2) in a serum." The patent claims a method of diagnosing cancer in an individual by measuring the expression of des-R-prothrombin activation peptide fragment F2 in blood, serum and plasma samples. According to the patent, the expression may be measured using a kit or biochip containing antibodies specifically binding to des-R prothrombin activation peptide fragment F2. By comparing the measured expression level of des-R-prothrombin activation peptide fragment F2 in the sample of the test subject with a normal subject, the inventors believe that they can determine if the subject has a cancer.


Theranos of Palo Alto, Calif., has received US Patent No. 8,435,738, "Systems and methods for multi-analysis." The patent describes a system that consists of modules mounted on a support structure. According to the patent, these modules include a sample preparation station, an assay station, an a detection station. The system is configured to perform sample preparation procedures and multiple types of assays, such as immunoassays, nucleic acid assays, receptor-based assays, and others. According to the patent, the multiple types of assays are performed with the aid of isolated units contained within the system.

The Scan

Pig Organ Transplants Considered

The Wall Street Journal reports that the US Food and Drug Administration may soon allow clinical trials that involve transplanting pig organs into humans.

'Poo-Bank' Proposal

Harvard Medical School researchers suggest people should bank stool samples when they are young to transplant when they later develop age-related diseases.

Spurred to Develop Again

New Scientist reports that researchers may have uncovered why about 60 percent of in vitro fertilization embryos stop developing.

Science Papers Examine Breast Milk Cell Populations, Cerebral Cortex Cellular Diversity, Micronesia Population History

In Science this week: unique cell populations found within breast milk, 100 transcriptionally distinct cell populations uncovered in the cerebral cortex, and more.