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IP Roundup: Affymetrix, University of Colorado, Genisphere, Roche, Population Diagnostics

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Title: Automated method of manufacturing polymer arrays.
Patent Number: 8,652,774
Filed: Oct. 4, 2005
Lead Inventor: Melvin Yamamoto, Affymetrix


Title: Use of photopolymerization for amplification and detection of a molecular recognition event.
Patent Number: 8,652,778
Filed: April 8, 2011
Lead Inventor: Christopher Bowman, University of Colorado


Title: Methods and kits for nucleic acid amplification.
Patent Number: 8,653,251
Filed: Jan. 25, 2011
Lead Inventor: Robert Getts, Genisphere


Title: Scoring system for the prediction of cancer recurrence.
Patent Number: 8,655,597
Filed: April 13, 2010
Lead Inventor: Maasaki Oka, Roche


Title: Evaluating genetic disorders.
Patent Number: 8,655,599
Filed: April 27, 2011
Lead Inventor: James Chinitz, Population Diagnostics

The Scan

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.

TB Resistance Insights Gleaned From Genome Sequence, Antimicrobial Response Assays

Researchers in PLOS Biology explore M. tuberculosis resistance with a combination of sequencing and assays looking at the minimum inhibitory concentrations of 13 drugs.

Mendelian Disease Genes Prioritized Using Tissue-Specific Expression Clues

Mendelian gene candidates could be flagged for further functional analyses based on tissue-specific transcriptome and proteome profiles, a new Journal of Human Genetics paper says.

Single-Cell Sequencing Points to Embryo Mosaicism

Mosaicism may affect preimplantation genetic tests for aneuploidy, a single-cell sequencing-based analysis of almost three dozen embryos in PLOS Genetics finds.