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IP Roundup: Mar 23, 2010

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Covance of Princeton, NJ, has received US Patent No. 7,682,572, "Frozen tissue microarray." The patent describes a tissue microarray composed of frozen tissue cores that extend from the top of the tissue microarray to a release. According to the patent, the release is a material from which embedding material of the tissue microarray can easily be removed. A stiffener is used with the release to maintain its flat shape. By using the release, cores of frozen embedding material can be removed from the tissue microarray during the process of inserting donor tissue cores into the embedding material of the tissue microarray, the inventors state.


Affymetrix has received US Patent No. 7,682,782, "System, method, and product for multiple wavelength detection using single source excitation." The patent describes a method for adjusting the system gain of an array scanner for a number fluorophore species. The method includes setting an excitation beam at a first power level that elicits an optimal signal-to-noise ratio response from a first fluorophore species; scanning an array with the excitation beam; setting the excitation beam at a second power level different than the first power level; and scanning the array with the excitation beam.


Corning of Corning, NY, has received US Patent No. 7,682,802, "Assay solution compositions and methods for GPCR arrays." The patent claims buffered assay solutions for performing binding or functional assays on G protein-coupled receptor arrays. According to the patent, the buffered assay solution is composed of a buffer reagent; an inorganic salt of either a monovalent or divalent species; and an optional combination of a blocker reagent or a protease-inhibitor.


Stanford University has received US Patent No. 7,682,837, "Devices and methods to form a randomly ordered array of magnetic beads and uses thereof." The patent claims devices and methods for forming and using random arrays of magnetic particles. It provides a chip with magnetic domains that produce localized magnetic fields capable of immobilizing magnetic particles. Probe or sensor molecules can be coupled to the beads, which are then dispersed on the chip, forming a random-order array.


Stanford University has received US Patent No. 7,682,838, "Magnetic nanoparticles, magnetic detector arrays, and methods for their use in detecting biological molecules." The patent describes magnetic nanoparticles that can be attached to nucleic acid molecules. These molecules are then captured by a complementary sequence attached to a detector, such as a spin valve detector or a magnetic tunnel junction detector, according to the patent.

The Scan

NFTs for Genome Sharing

Nature News writes that non-fungible tokens could be a way for people to profit from sharing genomic data.

Wastewater Warning System

Time magazine writes that cities and college campuses are monitoring sewage for SARS-CoV-2, an approach officials hope lasts beyond COVID-19.

Networks to Boost Surveillance

Scientific American writes that new organizations and networks aim to improve the ability of developing countries to conduct SARS-CoV-2 genomic surveillance.

Genome Biology Papers on Gastric Cancer Epimutations, BUTTERFLY, GUNC Tool

In Genome Biology this week: recurrent epigenetic mutations in gastric cancer, correction tool for unique molecular identifier-based assays, and more.