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IP Roundup: Dec 8, 2009


Accelr8 Technology of Denver has received US Patent No. 7,629,029, "Functional surface coating." The patent claims methods of preparing functional thin films or surface coatings with low non-specific binding. According to the patent, the thin films contain specified functional groups and non-specific binding repellant components. The thin films are either covalently bound to or passively adsorbed to various solid substrates. The specified functional group provides specified activity for the thin-film-modified solid surfaces, and non-specific binding repellant components reduce the non-specific binding to the thin-film-modified solid surfaces. Non-specific binding repellant components do not affect specified functional group's activity in the thin films.

Honeywell International of Morristown, NJ, has received US Patent No. 7,629,115, "Cell-based platform for high throughput screening." The patent describes an apparatus for testing multiple sample compounds for their biological effect. The apparatus includes a porous block with planar top and bottom surfaces. The top surface has cell adhesive regions and cell dis-adhesive regions and the bottom surface provides multiple sites to load the sample compounds. These sites are located opposite from the cell adhesive regions on the top surface of the porous block.

Affymetrix has received US Patent No. 7,629,164, "Methods for genotyping polymorphisms in humans." The patent provides nucleic acid sequences that are complementary to a collection of human single nucleotide polymorphisms. The method provides the sequences in such a way as to make them available for a variety of analyses including genotyping a large number of SNPs in parallel by, for example, allele-specific hybridization. The patent also provides a collection of human SNPs that is useful for genetic analysis within and across populations.

of Corning, NY, has received US Patent No. 7,629,173, "Optical reader system and method for monitoring and correcting lateral and angular misalignments of label independent biosensors." The patent claims an optical reader system and method that can detect a lateral and/or angular misalignment of one or more biosensors so that the biosensors can be properly re-located after being removed from and then reinserted into the optical reader system. In one embodiment, the biosensors are incorporated within the wells of a microplate.

The Kitasato Institute and the National Institute of Technology and Evaluation of Japan have received US Patent No. 7,630,836, "Polynucleotides." The patent claims polynucleotides derived from microorganisms belonging to actinomycetes, polypeptides encoded by the polynucleotides, polynucleotide arrays composed of the polynucleotides, and recording media in which the nucleotide sequences of the polynucleotide are readable in a computer.

The Scan

US Supports Patent Waivers

NPR reports that the Biden Administration has announced its support for waiving intellectual property protections for SARS-CoV-2 vaccines.

Vaccines Versus Variants

Two studies find the Pfizer-BioNTech SARS-CoV-2 vaccine to be effective against viral variants, and Moderna reports on booster shots to combat variants.

CRISPR for What Ails You

The Wall Street Journal writes that CRISPR-based therapies could someday be used to treat common conditions like heart attacks.

Nature Papers Review Integration of Single-Cell Assay Data, Present Approach to Detect Rare Variants

In Nature this week: review of ways to integrate data from single-cell assays, and more.