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NEW YORK (GenomeWeb) – Variants within the human leukocyte antigen (HLA) locus are likely the most important for predicting whether a kidney transplant will be successful, a new study has found.

While kidney transplant outcomes have improved over the past decade, there are a number of factors that affect long-term outcomes, including HLA mismatch. The HLA gene complex helps the immune system tell friend from foe, and close matches are needed in organ transplants to limit rejection.

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