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Funding Update: NSF Microarray Grants 2013

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NSF Microarray Grants Awarded Jan 1 — June 25, 2013

Handheld multiplex immunoassay microfluidic device for water-based toxin detection
Start Date: Jan. 1, 2013
Expires: Dec. 31, 2013
Awarded amount to date: $149,180
Principal investigator: Hong Jiao
Sponsor: HJ Science & Technology

The investigators are developing an enzyme-linked immunosorbent assay that is run in a microfluidic device, and can be used in the environmental monitoring of harmful algal bloom toxins.


Personalized point-of-care immunity assessment platform
Start Date: Jan. 1, 2013
Expires: June 30, 2013
Awarded amount to date: Not available.
Principal investigator: Michael Harvey
Sponsor: Maine Manufacturing

The researchers intend to create a plasma-generating multiplexed epitope-specific test device for testing immunity to viral diseases, based on peptide array and epitope mapping technology.


New fluorescent biosensors for signaling in living cells
Start Date: Jan. 1, 2013
Expires: Dec. 31, 2013
Awarded amount to date: $164,423
Principal investigator: Anne Quinn
Sponsor: Montana Molecular

The investigators will explore the feasibility of developing a genetically-encoded biosensor to monitor levels of cyclic adenosine monophosphate, a second messenger component of drug signaling pathways.


Multifunctional nanobiointerfaces for sensing applications
Start Date: Feb. 1, 2013
Expires: Jan. 31, 2015
Awarded amount to date: $299,955
Principal investigator: Aleksandr Simonian
Sponsor: Auburn University

The investigators intend to develop a new device capable of multianalyte detection based on cascading layers on a single electrode. They see this approach as an alternative to multi-electrode arrays that rely on "complicated microfluidics" and "heavy computing."


Multichannel disposable sensors for animal health disease diagnostics
Start Date: May 15, 2013
Expires: April 30, 2016
Awarded amount to date: $358,393
Principal investigator: Eric Vogol
Sponsor: Georgia Tech Research

The investigators will develop a low-cost multiplexed electrochemical platform capable of detecting several antibody markers related to bovine respiratory disease infections.


Crosstalk-free multiplexed immunoassay of plasma biomarkers
Start Date: July 1, 2013
Expires: Dec. 31, 2015
Awarded amount to date: $149,715
Principal investigator: Arlyne Simon
Sponsor: PhasiQ

The investigators plan to develop and commercialize a test that monitors and quantifies levels of multiple proteins in biological fluids, targeting biomarkers that indicate disease onset, disease progression, or drug efficacy.


Polymer electrosonic actuation microarray: Low-cost tool for transfection of biological cells
Start Date: July 1, 2013
Expires: June 30, 2014
Awarded amount to date: $225,000
Principal investigator: John Meacham
Sponsor: OpenCell Technologies

The investigators intend to design and optimize a polymer microarray and to develop a low-cost system capable of generating the mechanical stress field needed to achieve improved treatment outcomes in difficult-to-transfect cells.


Microwell array plates for dual-mode screening of bead libraries
Start Date: July 1, 2013
Expires: Dec. 31, 2013
Awarded amount to date: $150,000
Principal investigator: Vladislav Bergo
Sponsor: Adeptrix

According to investigators, this project, if successful, will yield microchips with dual optical and mass spectrometry readouts that will enable the development of new methods of high-throughput screening and support the use of mass spectrometry in various HTS-based applications.

The Scan

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NFT of the Web

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23andMe on the Nasdaq

23andMe's shares rose more than 20 percent following its merger with a special purpose acquisition company, as GenomeWeb has reported.

Science Papers Present GWAS of Brain Structure, System for Controlled Gene Transfer

In Science this week: genome-wide association study ties variants to white matter stricture in the brain, and more.