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NEW YORK (GenomeWeb) – A team led by researchers in Germany has tracked down copy number profiles that appear to correspond to poorer-than-usual outcomes in individuals with a form of liver cancer called intrahepatic cholangiocarcinoma (iCCA).

Using genome-wide array comparative genomic hybridization, the researchers searched for informative copy number alterations in 37 primary iCCA samples and more than a dozen matched lymph node metastases. Prior research suggested that lymph node metastases coincided with significantly poorer survival times in iCCA patients, they noted.

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