NEW YORK (GenomeWeb) – A new genome-wide association study has highlighted hundreds of new and known loci with ties to low bone mineral density (BMD), a well-recognized risk factor for osteoporosis and associated bone breaks, leading to a proposed polygenic risk score for osteoporosis.

"Knowledge of one's genetic risk for low BMD could be combined with clinical risk factors to identify patients, athletes, or military personnel at high risk for osteoporosis and fracture," wrote the study's sole author Stuart Kim, a developmental biology researcher at Stanford University.

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In PNAS this week: de novo NUS1 mutations linked to Parkinson's disease risk, candidate hepatocellular carcinoma drivers, and more.

Oct
25
Sponsored by
Roche

This webinar will detail a comprehensive strategy that a lab has put in place to evaluate  NGS oncology assays for genomic tumor profiling of plasma and tissue samples.