Microarrays & Multiplexing
News on microarrays, multiplexing, genotyping, cytogenetics, gene expression profiling in genetics, genomics, and molecular diagnostics.
Polygenic Risk Score Performance Improved With Expression-Related Rare Variant Insights
Using an independent outlier gene count score, investigators found that rare variants linked to gene expression outlier effects can improve polygenic risk score predictions.
Hearing Loss GWAS Meta-Analysis Highlights Cochlear Structure Role in Hearing Impairment
Investigators saw a role for the stria vascularis in hearing loss with genetic data for 147,997 hearing loss cases and 575,269 controls, coupled with follow-up functional analyses in mice.
Type 2 Diabetes Multi-Ancestry GWAS Enables Risk Prediction Across Populations
With data for more than 180,800 cases and some 1.2 million controls, researchers found hundreds of genetic risk loci and developed multi-ancestry risk scores.
SomaLogic Q1 Revenues Grow 22 Percent
The Boulder, Colorado-based protein analysis company missed the consensus Wall Street revenue estimate but beat it on the bottom line.
Sibling-Informed GWAS Distinguishes Between Direct Genetic Effects on Traits, Biases
With data on 178,086 siblings, researchers searched for direct genetic contributors to 25 phenotypes, comparing them to population-based GWAS signals.