Microarrays & Multiplexing
News on microarrays, multiplexing, genotyping, cytogenetics, gene expression profiling in genetics, genomics, and molecular diagnostics.
Polygenic Risk Score Addition Does Not Improve Models Predicting Schizophrenia Prognosis
The findings highlight the need for polygenic risk scores to not only be predictive but also provide additional information that cannot be captured elsewhere more easily.
Consortium Catalogs Variants Affecting Blood Gene Expression
Members of the eQTLGen Consortium turned to data for almost 31,700 individuals to define local and distant expression quantitative trait loci affecting gene expression in the blood.
Acute Lymphoblastic Leukemia Risk Linked to Genetically Mediated Increase in Lymphocyte Count
A team led by researchers at the University of Southern California analyzed genetic links between blood cell traits and ALL susceptibility in children.
At ESHG, DeCode Genetics Highlights Integration of Proteomics, Genomics for Disease Research
DeCode has identified markers associated with osteoarthritis and autoimmune thyroid disease and is developing a calculator to predict five-year mortality risk.
Osteoarthritis GWAS Leads to Key Genes, Treatment Targets
With a genome-wide association study and functional follow-up analyses, investigators saw 100 osteoarthritis-related loci including variants in potentially targetable genes and pathways.