Microarrays & Multiplexing

News on microarrays, multiplexing, genotyping, cytogenetics, gene expression profiling in genetics, genomics, and molecular diagnostics.

Genetic Disease Risk Estimates May Be off in Populations Not Covered by GWAS

A Georgia Tech team found that the reliance of genome-wide association studies on European populations has skewed estimates of disease risk in other populations.

Non-Cancerous Prostate Disease GWAS Uncovers PSA Level-Linked Variants

At least some variants associated with benign prostatic hyperplasia appeared to contribute to PSA levels in the blood, independent of prostate cancer.

Roche Developing Digital PCR Platform

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Roche said at the AMP annual meeting that it plans to commercialize the system in Europe with CE IVD marking for clinical applications and in the US with a 510(k) exemption.

Osteoarthritis Risk Linked to Novel Genetic Loci

The researchers noted ties between osteoarthritis-linked variants and height, and found one risk loci that implicated the Hedgehog signaling pathway.

NanoString, MacroGenics Collaborate to Identify, Develop Immuno-Oncology Biomarkers

The firms have agreed to conduct joint research using NanoString's PanCancer IO 360 panel to explore predictive signatures for MacroGenics' MGD013 clinical applications.

Oct 25, 2018

Leica Biosystems, Ultivue to Comarket Platforms for Biomarker Detection

Oct 25, 2018

Stroke Risk Tied to Genetics, Lifestyle in UK Biobank Analysis

Oct 24, 2018

Illumina Points to Clinical Sequencing, Consumer Genomics for Future Growth

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Oct 23, 2018

Illumina Revenues Increase 20 Percent in Q3

Oct 23, 2018

Warfarin Bleeding Risk SNPs Identified in African Americans

Oct 22, 2018

GeneATLAS Database Documents Diverse Trait Associations Detected With UK Biobank Data

Oct 19, 2018

Low-Frequency Genetic Variations Contribute to Multiple Sclerosis Risk

Oct 16, 2018

Team Taps Large Population PheWAS For Clues to Drug Targets, Side Effects

Oct 15, 2018

Diagnomics, Translational Software Ink Partnership on PGx Test Reports

Oct 11, 2018

Multiple Myeloma Subtypes Linked to Patients' African Ancestry

Oct 11, 2018

Researchers Explore Variety of Response Markers in Melanoma Study of Combo Checkpoint Inhibitors

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Oct 10, 2018

UK Biobank Project Researchers Publish Full Genomic, Phenotypic Resource

Oct 04, 2018

Blue Eyes of Siberian Huskies Result from DNA Duplication, GWAS Finds

Oct 04, 2018

Mendelian, Common Disease Links Detected From GWAS Data

Oct 02, 2018

New Chronic Kidney Disease Pathways Emerge From Integrated Tissue-Specific Genetic Analysis

Oct 01, 2018

Evonetix, LioniX International Partner to Produce Prototype DNA Synthesis Systems

Oct 01, 2018

Blood Lipid GWAS, PheWAS Leads to Drug Target Gene

Sep 27, 2018

Chronic Back Pain Linked to Three Loci in New Genome-Wide Analysis

Sep 26, 2018

GWAS Reveals Common, Polygenic Contributors to Neurodevelopmental Disorders

Sep 25, 2018

Acute Sleep Deprivation Linked to Shift in Blood-Based Gene Expression

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The Scan

Draft Brexit on the Table

Though many details have yet to be worked out, the draft deal for the UK's withdrawal from the EU is giving researchers some hints for what they can expect, Nature News says.

'Really Just a Titi Monkey'

DNA testing has solved a 100-year-old mystery contained in the skull and teeth samples of a now-extinct monkey that once inhabited Jamaica, Gizmodo reports.

Hold the GMO Mosquitoes

As the UN ponders a ban on gene drives, one malaria researcher says there are less dramatic ways to fight the disease in Africa than unleashing GM mosquitoes on a whole continent.

This Week in Nature

In Nature this week: an improved reference genome of the Aedes aegypti mosquito, genomes of four species of truffles, and more.

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