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Metabolic Disease

News on research and diagnostics for metabolic disorders and metabolic diseases.

A prospective metagenomic sequencing study searched for viral changes in children who developed islet autoimmunity or type 1 diabetes, revealing coxsackievirus ties to autoimmunity.

Researchers linked 16 genetic loci to diabetic kidney disease, including a common missense mutation in the COL4A3 gene that appears to be protective.

A Mendelian randomization analysis found visceral fat to be linked to cardiometabolic disease risk, especially type 2 diabetes risk in women.

Different biological processes appear to drive body mass index during infancy and later in childhood and adulthood, which could inform obesity prevention strategies.

A gene-environment study involving more than 18,000 individuals suggests jogging and other forms of exercise may modify the genetic risk for obesity.

Gene editing could be an issue competitive sports need to address soon, four researchers from Arizona State University write at Slate.

A genetic alteration appears to increase heart failure risk among people of African descent, according to the Washington Post.

In his look back at the past decade, BuzzFeed News' Peter Aldhous writes that direct-to-consumer genetic testing has led to "Facebook for genes."

In Nature this week: genetic "clock" that can predict the lifespans of vertebrates, new assembler called wtdbg2, and more.