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Vincent Fusaro: Transforming Translational Medicine

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Recommended by: Mark Boguski, Harvard Medical School

Vincent Fusaro is attempting to advance translational medicine using computational methods. This year, he received a K99/R00 Pathways to Independence grant from the National Library of Medicine to pursue this line of research and identify new uses for current drugs and then confirm their benefit using electronic medical records from health-care providers.

Also this year, Fusaro reported the results of a clinical trial simulation framework to model warfarin dosing and the International Normalization Ratio at the National Library of Medicine Informatics Training Conference.

For Fusaro, the Holy Grail of data would be full genomic data linked with full phenotype data across all individuals. "In collaboration with the Harvard hospitals, we've launched new initiatives to collect this information with proper patient consent," he says. "This would allow us to correlate genomic information with patient outcomes and help us understand which mutations are important for clinical treatment and which are part of the incidentalome."

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