Vertex Says CF Patients with Double F508del Mutation Showing Improvement in VX-809/Kalydeco Trial | GenomeWeb

Vertex Pharmaceuticals has announced positive interim results this month from the second part of an ongoing Phase II trial examining a combined regimen of its approved drug Kalydeco and its newer treatment VX-809 in cystic fibrosis patients with the F508del mutation. After 56 days of treatment, adult subjects homozygous for the mutation have shown significant improvement in lung function, the company said.

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