Team IDs SNP Explaining Some Poor Response to Asthma Therapy, Continues Work Toward Predictive Panel | GenomeWeb

By Molika Ashford

Researchers from Brigham and Women's Hospital have identified a mutation in the glucocorticoid-induced transcript 1 gene that is associated with poor response to commonly prescribed inhaled glucocorticoid asthma therapies.

The variant only accounts for about six and a half percent of the overall variability in response to glucocorticoid treatment, however, so the researchers are now expanding their search to find additional SNPs that could be combined into a predictive panel.

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