By Turna Ray

Roche recently presented data showing that its PCR-based Cobas BRAF Mutation Test is more sensitive than Sanger sequencing in selecting which patients will benefit from its melanoma drug Zelboraf — a move aimed at convincing labs to replace their standard laboratory-based testing methods with the US Food and Drug Administration-approved companion diagnostic.

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In PNAS this week: spatiotemporal study of lncRNA expression, role of extrachromosomal, circular DNAs in yeast, and more.

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