Originally published Dec. 12.

Plexxikon said this week that it is launching a Phase I/II trial to study the safety and efficacy of its drug candidate PLX3397 in AML patients whose tumors harbor cancer-driving Flt3 mutations, which occur in 20 percent to 30 percent of AML patients.

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The US Food and Drug Administration has approved Kite Pharmaceuticals' CAR T-cell therapy for large B-cell lymphomas, the New York Times reports.

Kaiser Health News reports that gene therapies could cost more than a million dollars.

Worcester Polytechnic Institute researchers have received a grant to combine biology and computer science for high school students.

In Nature this week: variants associated with obsessive-compulsive disorder, review of key CRISPR enzymes, and more.