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Pairings: Oct 12, 2011

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Exosome Diagnostics has made three appointments to its executive team, including appointing David Okrongly to be chief operating officer, Michael Donovan to be chief medical officer, and Sally Bowden to be director of regulatory affairs. The company also named Raphael Bueno, associate chief of cardiothoracic surgery at Harvard University, and Michael Manyak, executive director of global medical affairs at GlaxoSmithKline, to its scientific advisory board.

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The Scan

Study Tracks Responses in Patients Pursuing Polygenic Risk Score Profiling

Using interviews, researchers in the European Journal of Human Genetics qualitatively assess individuals' motivations for, and experiences with, direct-to-consumer polygenic risk score testing.

EHR Quality Improvement Study Detects Demographic-Related Deficiencies in Cancer Family History Data

In a retrospective analysis in JAMA Network Open, researchers find that sex, ethnicity, language, and other features coincide with the quality of cancer family history information in a patient's record.

Inflammatory Bowel Disease Linked to Gut Microbiome Community Structure Gradient in Meta-Analysis

Bringing together data from prior studies, researchers in Genome Biology track down microbial taxa and a population structure gradient with ties to ulcerative colitis or Crohn's disease.

Ancient Greek Army Ancestry Highlights Mercenary Role in Historical Migrations

By profiling genomic patterns in 5th century samples from in and around Himera, researchers saw diverse ancestry in Greek army representatives in the region, as they report in PNAS.