Jackson Lab Collecting Cancer Mutation Data in Mouse Avatars to Support PGx Studies | GenomeWeb

The Jackson Laboratory's patient-derived xenograft, or PDX, mouse program has begun sequencing samples from a growing collection of mice implanted with human tumor tissue to support studies of molecularly targeted drugs.

The Jax PDX mice are currently used to test drug efficacy and mechanism of action, but the lab hopes that these mouse avatars will serve in the future as a way to test therapies in real time to personalize patient treatment.

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