By Turna Ray

In unanimously invalidating Prometheus Laboratories' patent clams on gauging metabolites to dose thiopurine drugs, the US Supreme Court this week indicated that merely using "well-understood, routine, conventional" methods to correlate naturally occurring biological processes to treatment decisions isn't patent eligible — a ruling that is likely to have a broad impact on diagnostics developers and the personalized medicine field.

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Harold Varmus, the director of the National Cancer Institute, has announced that he is stepping down after nearly five years.

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