The Clinic Draws Near


In melanoma patients, resistance to BRAF inhibitors and the development of secondary tumors after treatment may be due to mutations in RAS, according to a study published in the January issue of the New England Journal of Medicine. In a related editorial in the same issue, the Wistar Institute's Ashani Weeraratna described BRAF inhibition as a good example of when a tailored treatment is necessary. She recommended that patients taking BRAF inhibitors be tested and their RAS status determined to reduce the risk of secondary tumors.

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Researchers test gene therapy targeting a different cancer protein in a new trial, the New York Times reports.

Pennsylvania State University researchers found that salivary microRNAs could predict which kids would have longer concussion symptoms, according to NPR.

The Associated Press reports Alex Azar, the new Department of Health and Human Services secretary nominee, made millions of dollars as a pharmaceutical executive.

In PNAS this week: immune profiling of breast cancer, transposable element patterns in rice, and more.