CHMP Recommends EU Approval of Roche PGx Drug Zelboraf | GenomeWeb

The European Commission's Committee for Medicinal Products for Human Use last eek recommended marketing authorization for Roche's Zelboraf as a monotherapy for the treatment of patients with BRAF V600 mutation-positive unresectable or metastatic melanoma.

Zelboraf (vemurafenib) inhibits BRAF proteins that harbor a mutation at position 600, which causes cell proliferation in the absence of growth factors that would normally be required for proliferation.

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