MCW Lab Lands $8.7M to Create Knockout Rats for Modeling Disease Genetics | GenomeWeb

NEW YORK (GenomeWeb News) – A team at the Medical College of Wisconsin will use a five-year, $8.7 million grant from the National Heart, Lung, and Blood Institute to create new genetically modified rat models for studying genetics of human diseases, MCW said today.

Principal investigator Howard Jacob, director of MCW's Human and Molecular Genetics Center, will lead the effort using transcription activator-like effector nuclease gene editing technology to develop 200 gene-targeted knockout rat models and to disseminate them throughout the disease research community.

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