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Kinaxo, Bayer Vital Collaborate To Look for Cancer Treatment Biomarkers

NEW YORK (GenomeWeb News) – The German biotech company Kinaxo Biotechnologies, a spinout of the Max Planck Institute, and Bayer Vital announced today that they have formed a collaboration to identify novel phosphoproteomics biomarkers for predicting cancer treatment outcomes.

The researchers plan to use Kinaxo's quantitative phosphoproteomics technology, PhosphoScout, to find and quantify phosphorylation sites as part of a clinical trial conducted by Bayer Vital on the use of oral anti-cancer drug sorafenib (Nexavar) in acute myeloid leukemia.

The drug, which has already been approved for treating hepatocellular carcinoma and renal cell carcinoma, is known to inhibit several kinases involved in pathways governing cellular growth and blood vessel formation.

For the current study, the team plans to use phosphoproteomics approaches to look at how cellular phosphorylation patterns change in response to drug treatment and to try to find biomarkers for predicting treatment outcomes.

"Both partners aim at investigating innovative technologies (such as phosphoproteomics) and targeted therapies (such as kinase inhibitors) which — in conjunction — should allow more effective cancer treatments and, thus, provide more hope to cancer patients," Erich Enghofer, head of Bayer Healthcare's oncology business unit, said in a statement.

The Scan

US Booster Eligibility Decision

The US CDC director recommends that people at high risk of developing COVID-19 due to their jobs also be eligible for COVID-19 boosters, in addition to those 65 years old and older or with underlying medical conditions.

Arizona Bill Before Judge

The Arizona Daily Star reports that a judge is weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.