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Integrative Proteomics, University of Toronto to Study Bacterial Proteomes

NEW YORK, Oct. 1 – Integrative Proteomics and the University of Toronto are leading a team of researchers to study protein interactions in certain pathogenic bacteria, Integrative Proteomics said on Monday.

A pair of non-profit Canadian corporations, Genome Canada and the Ontario Research and Development Challenge Fund, will also contribute to the research project. Together, the four parties have pledged a combined $9 million for the initiative. 

The joint effort, led by Jack Greenblatt, a professor of medical research at the University of Toronto and co-founder of Integrative Proteomics, will use mass spectrometry resources at the university and at Integrative Proteomics to study how proteins from the bacteria interact.

“Our combined efforts will generate information about protein complexes of pathogenic bacteria at a scale the academic research world could never have contemplated without the industrial partnership of [Integrative Proteomics]," Greenblatt said in a statement. “Our collaborative efforts will generate genome-scale biological information to create comprehensive 'network diagrams' for the nano-biomachines of entire organisms."

Integrative Proteomics, founded in August 2000 and also based in Toronto, has built facilities to study protein interactions using mass spectrometry, nuclear magnetic resonance, and X-ray crystallography.

In an arrangement announced in May with Bruker Daltonics, Bruker BioSpin, and Bruker AXS, the Bruker companies provided scientific equipment and equity financing in exchange for an equity stake in Integrative Proteomics.  

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