2005 may be remembered as a turning point in the commercial life science informatics sector. While the year marked the end of a period of rapid consolidation that began in 2002, it also ushered in a rash of niche application areas that may pose a number of technical and business challenges for a market that is already highly fragmented.

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CNBC reports that Amazon invested in the startup Grail as it sees an opportunity for its cloud computing company in genomics.

Lawrence Krauss writes at Slate that science is needed for good public policy and should not be ignored.

Researchers are working on re-making the yeast genome from scratch, according to the Associated Press.

In Cell this week: functional profiling of Plasmodium genome, a self-inactivating rabies virus, and more.