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Xpression NTI, STACKdb, GeneSpring


InforMax of Bethesda, Md., has released a new desktop application for the analysis of gene expression data, Xpression NTI, as well as the latest upgrade to its Vector NTI Suite.

Xpression NTI provides a variety of algorithms for the processing and analysis of data from single and multiple microarray expression experiments. Filtering, sorting, clustering, parameterization, or profiling methods can be used to analyze and organize data.

Version 7.0 of the Vector NTI sequence analysis and data management software package offers increased functionality across all of the suite application programs — Vector NTI, AlignX, BioPlot, and ContigExpress. According to InforMax, notable enhancements include optimized recombinant strategies and protocols, enhanced primer design and analysis capabilities, an enhanced Blast viewer for customized visualization of sequence data, and improved utilities for sequence alignment and contig assembly.


Electric Genetics and the South African National Bioinformatics Institute have released version 3.0 of the STACKdb human gene expression index. The latest version incorporates mRNA sequences and web-based visualization software.

STACKdb v3.0 offers an increase of 569,014 new EST sequences and 51,638 mRNA sequences over STACKdb v2.4. The database is now distributed in two forms: relational database tables, for use with the viewing software, and FastA files for use with external programs.

Academic and non-profits may register at to download STACKdb v3.0.


Silicon Genetics, based in Redwood City, Calif., will now market the ArrayMiner clustering algorithm from Brussels-based Optimal Design for use with its GeneSpring gene expression analysis software. ArrayMiner uses genetic algorithms to cluster gene expression data.

Silicon Genetics is offering an evaluation of ArrayMiner through


Alexander Kozik of the Department of Vegetable Crops at the University of California at Davis has made PhyloGrapher — a program designed to visualize and study evolutional relationships between families of homologous genes or proteins — freely available at

PhyloGrapher is a drawing tool that generates custom graphs out of the given set of genes.

Biobase of Wolfenb¸ttel, Germany, has released Cytomer, a database describing a hierarchical classification structure for physiological systems, organs, and cell types. According to Biobase, Cytomer can be used to map gene expression data to its expression sources.


Filed under

The Scan

Possibly as Transmissible

Officials in the UK say the B.1.617.2 variant of SARS-CoV-2 may be as transmitted as easily as the B.1.1.7 variant that was identified in the UK, New Scientist reports.

Gene Therapy for SCID 'Encouraging'

The Associated Press reports that a gene therapy appears to be effective in treating severe combined immunodeficiency syndrome.

To Watch the Variants

Scientists told US lawmakers that SARS-CoV-2 variants need to be better monitored, the New York Times reports.

Nature Papers Present Nautilus Genome, Tool to Analyze Single-Cell Data, More

In Nature this week: nautilus genome gives peek into its evolution, computational tool to analyze single-cell ATAC-seq data, and more.