Skip to main content
Premium Trial:

Request an Annual Quote

XDx to Use Ingenuity Software to Better Understand Gene Expression Tied to Immunity

NEW YORK (GenomeWeb News) — XDx, a molecular diagnostics company specializing in the immune system, has licensed Ingenuity Systems’ software, Ingenuity said today.
The IPA 5.0 software is used to “model, analyze, and understand” biological and chemical systems, Ingenuity said.
XDx measures gene expression in patient blood to monitor the immune system. Ingenuity said the IPA 5.0 enables users to “apply filters to their data to determine whether a particular gene or protein is detectable in sentinel tissues or other bodily fluids. ...."
Tod Klingler, vice president of Informatics at XDx, said in a statement that the software “provides us with access to its extensive knowledge base of gene function information assembled from the scientific literature through easy-to-use tools that our researchers can use to rapidly evaluate candidate biomarkers. Specifically, IPA allows us to make sense of our gene expression data in the context of known immune system interactions and pathways."
Financial terms of the agreement were not released.

The Scan

Germline-Targeting HIV Vaccine Shows Promise in Phase I Trial

A National Institutes of Health-led team reports in Science that a broadly neutralizing antibody HIV vaccine induced bnAb precursors in 97 percent of those given the vaccine.

Study Uncovers Genetic Mutation in Childhood Glaucoma

A study in the Journal of Clinical Investigation ties a heterozygous missense variant in thrombospondin 1 to childhood glaucoma.

Gene Co-Expression Database for Humans, Model Organisms Gets Update

GeneFriends has been updated to include gene and transcript co-expression networks based on RNA-seq data from 46,475 human and 34,322 mouse samples, a new paper in Nucleic Acids Research says.

New Study Investigates Genomics of Fanconi Anemia Repair Pathway in Cancer

A Rockefeller University team reports in Nature that FA repair deficiency leads to structural variants that can contribute to genomic instability.