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XD Bio Gets $150K NHGRI Grant to Develop Web Interface for ENCODE Project

NEW YORK — XD Bio said today that it has been awarded a six-month, $149,959 grant from the National Human Genome Research Institute to adapt its web-based genomic data analysis methods platform for computational analyses developed for the Encyclopedia of DNA Elements (ENCODE) project.

The platform, called Truwl, hosts bioinformatic tools, workflows, and data files to enable researchers to access and share DNA sequencing data and methods.

According to the grant's abstract, Whitefish, Montana-based XD will collaborate with the ENCODE Data Coordinating Center at Stanford University to expand Truwl to contain a new interface with dynamic forms for specifying pipeline inputs. A backend service will be created to execute and monitor compute jobs, and Google Cloud Platform compute instances will be created and configured with the ENCODE reproducibility framework to execute compute jobs.

The collaborators will use the ENCODE assay for transposase-accessible chromatin using sequencing pipeline to test the new interface, the abstract notes.