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Wisconsin Medical College Lab Releases SNP Tool


MADISON, Wis.--The Laboratory for Genetic Research at the Medical College of Wisconsin has designed a tool to assist researchers in selecting polymorphic markers for a genome scan of a cross between two strains. The Genome Scanner uses the laboratory’s Allele Characterization Project dataset in combination with the various genetic and radiation hybrid maps. The tool, which will eventually be housed within the Rat Genome Database, expected to be online by year’s end, is available now at

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The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

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Infectious Disease Tracking Study Compares Genome Sequencing Approaches

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LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.