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William Ladd, Charles Havekost, Karen Moore, Lee Bardwell, Heidi Hamm, Emmanuele DiBenedetto, Hod Lipson, Uri Alon


Genstruct has hired William Ladd as vice president of discovery systems. Ladd comes from Spotfire, where he was senior director of analytic applications. Prior to that, he was the director of bioinformatics methods at Gene Logic and led the statistical analysis efforts of the biological data department at Merck. At Genstruct, Ladd will lead development of the company’s Molecular Epistemics biological modeling platform.

The Department of Health and Human Services has appointed Charles Havekost as CIO and deputy assistant secretary for information resources management. Most recently, Havekost was the program manager for Prior to that, he was a director telecommunications firm BroadBand Office.

BioPoint Solutions has hired Karen Moore as CSO. Moore will be responsible for overseeing BioPoint’s DiscoverTrac data management and workflow technology. Moore was previously a consultant for Etiologics and CSO and co-founder of Hypnion. Prior to Hypnion, Moore helped design of laboratory-support IT solutions at Millennium Pharmaceuticals.

The National Academies Keck Futures Initiative has announced 11 recipients of its first Futures grants, each in the amount of $75,000, which support interdisciplinary research on cell signaling. Award recipients included Lee Bardwell of the University of California, Irvine, for a project entitled, “Intracellular Signaling Specificity: Theoretical and Computational Explorations;” Heidi Hamm and Emmanuele DiBenedetto of Vanderbilt University, for “Mathematical Models in Signaling Systems;” and Hod Lipson of Cornell University and Uri Alon of the Weizmann Institute of Science, for “Evolutionary Computation Methods for Inference of Signal Transduction Networks.”


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The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.