Skip to main content
Premium Trial:

Request an Annual Quote

Whitehead, MIT, NuGenesis Technologies, IDBS


Whitehead/MIT Team Finds Tiny RNA with New Software

Lee Lim, Christopher Burge, and colleagues from MIT and the Whitehead Institute report in the March 7 issue of Science a new computational method for detecting microRNAs — a class of noncoding RNAs around 22 nucleotides in length that control the expression of other genes at the post-transcriptional level.

The researchers used their software, called MiRscan, to identify 200-255 miRNA genes in the human genome. MiRscan takes a comparative genomics approach to identifying miRNA genes: It searches the human genome for segments similar to characteristic features of experimentally verified miRNA genes from several other species, including C. elegans and C. briggsae.

The researchers note that their estimate comprises around one percent of the predicted genes in humans — a similar portion to that seen for other large gene families with regulatory roles, such as those encoding transcription-factor proteins.


NuGenesis Partners with IBM

NuGenesis Technologies said last week that it had entered an agreement with IBM to co-market its SDMS (Scientific Data Management System) with IBM’s eServer and TotalStorage solutions.

SDMS is an application-independent, web-based platform that captures and stores analytical data from scientific instruments and third-party software.

According to NuGenesis, performance and scalability tests of SDMS running on IBM equipment indicate that over the course of a year, the combined solution provides the capability to archive 527 terabytes of data, or 110 million files of 5 megabytes each. A white paper with details of the tests is available at


IDBS Reports 14 Percent Growth in 2002 Revenues

IDBS, a privately held life science software company based in Guilford, UK, said last week that its revenues for the year ended December 31, 2002, increased 14 percent over 2001 revenues. The company did not provide further details on its revenues for either year.

IDBS attributed the growth in revenues to “substantial new sales” of its ActivityBase biology and chemistry data management software suite as well as its chemistry software applications.

Filed under

The Scan

Positive Framing of Genetic Studies Can Spark Mistrust Among Underrepresented Groups

Researchers in Human Genetics and Genomics Advances report that how researchers describe genomic studies may alienate potential participants.

Small Study of Gene Editing to Treat Sickle Cell Disease

In a Novartis-sponsored study in the New England Journal of Medicine, researchers found that a CRISPR-Cas9-based treatment targeting promoters of genes encoding fetal hemoglobin could reduce disease symptoms.

Gut Microbiome Changes Appear in Infants Before They Develop Eczema, Study Finds

Researchers report in mSystems that infants experienced an enrichment in Clostridium sensu stricto 1 and Finegoldia and a depletion of Bacteroides before developing eczema.

Acute Myeloid Leukemia Treatment Specificity Enhanced With Stem Cell Editing

A study in Nature suggests epitope editing in donor stem cells prior to bone marrow transplants can stave off toxicity when targeting acute myeloid leukemia with immunotherapy.