NEW YORK (GenomeWeb) – Transcription factors associated with cancer have been elusive drug targets. While there have been some serendipitous successes, the dynamics of DNA binding make them difficult to disrupt.

However, a new study suggests that an informatics-driven approach can find existing drugs that also block these proteins gone awry. And for anyone with access to several large data sets and the expertise to sift through them, more could be found, according to the study authors.

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360Dx reports that the US Centers for Medicare & Medicaid Services would cover next-generation sequencing-based cancer panel tests.

The Washington Post reports that a meteorologist is being considered as presidential science and technology advisor.

In PNAS this week: precision medicine strategy to screen for disease risk, genome evolution in Haemophilus influenzae, and more.

Researchers have developed a PCR-based assay to gauge whether manatees are present in waters.