BETHESDA, Md.--Scientists at the National Cancer Institute (NCI), the largest of the 17 biomedical research centers operated by the US National Institutes of Health, have spent the past decade crafting a bioinformatics program to facilitate the institute's efforts to discover cancer cures.
Since 1990, NCI has tested more than 70,000 compounds for activity against 60 cancer cell lines. At least 5 have entered human trials. More than 460,000 other compounds await testing. Along the way, NCI has developed an arsenal of diverse genomics-based drug discovery tools.