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Unleashed Informatics, Synamatix, BioImagene, Spotfire, Ingenuity, Jackson Lab, Scripps Florida


Unleashed Informatics Plans to Enforce BIND Patent

Unleashed Informatics issued a statement this week that it plans to enforce a patent it holds on the technology underlying the Biomolecular Interaction Network Database that was developed under the Blueprint Initiative at Mount Sinai Hospital in Toronto.

Unleashed said in the statement that it holds an exclusive commercial license for the patent, US No. 6,745,204, "System for electronically managing, finding, and/or displaying biomolecular interactions."

The patent abstract describes a computer-implemented system built on a database with a number of records. "Each record contains a reference biomolecular interaction defined by a chemical graph and descriptive information from an external database. The information correlates the biomolecular interactions to records in the external database. The system has a user interface allowing a user to selectively view information regarding a biomolecular interaction," the patent abstract states.

The company said in a statement that "for-profit organizations selling a biomolecular interaction software system or employing such a software system specification in a product for sale which falls under the claims of the above patent number will require a fee-based license from Unleashed Informatics."

The policy does not apply to academic or commercial users who access BIND through Unleashed's open access portal, the company said.

The company said that "affected organizations" must have licenses in place by June 1.

Synamatix Licenses SynaBase to Wash U Sequencing Center

Synamatix said this week that the Washington University Genome Sequencing Center has licensed its SynaBase database platform.

Wash U will use the system for quality control of data from newly sequenced genomes, Synamatix said.

Synamatix claims that SynaBase can store extremely large data sets without requiring additional hardware.

Financial terms of the agreement were not disclosed.

BioImagene to Integrate DMetrix Scanner with SIMS

DMetrix, a provider of glass slide digital imaging systems, said this week that it will integrate its DX-40 scanner with the Scientific Image Management System from BioImagene.

DMetrix, BioImagene, and IBM have already designed the first implementation of this combined system for the Arizona Cancer Center, DMetrix said. This implementation can accommodate up to 33 terabytes of image data and manage more than 100,000 high-resolution images. It runs on IBM's eServer xSeries systems, IntelliStation Z Pro viewing workstations, and TotalStorage DS4000 disk system.

Michael Descour, president of DMetrix, said in a statement that the configuration designed for the Arizona Cancer Center "serves as an outstanding template for any research environment that relies extensively on digital imagery."

Spotfire, Ingenuity to Integrate DecisionSite and IPA

Spotfire will integrate its DecisionSite software with Ingenuity Systems' Ingenuity Pathway Analysis, the companies said this week.

"Our customers have made significant investments in data-centric information technology. However, they lack the analytical tools that can be broadly deployed among researchers to quickly reveal comprehensive and actionable information," said Tuan Nguyen, vice president of partner and professional services at Ingenuity, in a statement.

NIGMS Awards Jackson Lab $15.1M to Create Systems Biology Center

The National Institute of General Medical Sciences said last week that it has awarded a team at the Jackson Laboratory $15.1 million under its National Centers for Systems Biology program.

The five-year award follows a $16.3 million grant that NIGMS awarded to the Institute for Systems Biology under the same program in March.

NIGMS said has funded five other systems biology centers over the last four years at Case Western Reserve University, Harvard University, the Massachusetts Institute of Technology, Princeton University, and the University of Washington.

The Jackson Lab will use the funding to create a Genome Dynamics center, which will study how patterns of genetic variation emerge and persist over time. The center will collect genetic information from more than 200 inbred strains of mice and will study expression patterns to identify co-expressed genes, examine how these patterns evolved, and investigate how the overall genome organization affects phenotype, NIGMS said

Gary Churchill, senior staff scientist at the Jackson Lab, is the principal investigator on the grant.

Dyadic Partners with Scripps Florida to Annotate Genome of C1 Fungus Genome

Dyadic International said this week that it will work with the Scripps Research Institute to provide a complete annotation of the genome of Chrysosporium lucknowense, Dyadic's proprietary fungal organism.

The organism, also known as C1, was sequenced last year by Agencourt Biosciences, a wholly owned subsidiary of Beckman Coulter.

The genome annotation work will be carried out at Scripps' new research center in Palm Beach County, Fla., under the direction of Nick Tsinoremas, senior director of Informatics at Scripps Florida, Dyadic said.

Financial details of the agreement were not disclosed.

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