Laboratories around the world are churning out gigabytes of notoriously messy microarray data, so why is a bioinformatics team at the University of Pittsburgh adding fake gene expression data to the mix? Because the last few years have produced an explosion of methods for analyzing microarray gene expression data, “but no standardization or metric by which those methods can be compared,” said James Lyons-Weiler, an assistant professor at the Center for Oncology Informatics at the University of Pittsburgh Cancer Institute.

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Microsoft co-founder Paul Allen also contributed to brain research, NPR reports.

The New York Times reports on the shifting interpretations of what some genetic variants mean over time.

In Cell this week: investigation of metastatic tumor evolution, more than 16,000 genetic variants introduced into the budding yeast model organism, and more.

MIT's Technology Review reports on Genentech's pursuit of personalized cancer vaccines.

Nov
05
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Sophia Genetics

With the Next Generation Sequencing (NGS), genomes sequencing has been democratized over the last decades with the detection of genomic alterations, thus replacing Sanger sequencing.