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Symyx Technologies, Elsevier, Nonlinear Dynamics, Japan’s National Cancer Research Institute, Organon, GeneGo

Symx Closes Deal to Buy MDL from Elsevier for $123M
Symyx Technologies said this week that it has closed its $123 million all-cash purchase of Elsevier’s MDL Information Systems business. Symyx said the final price will be subject to "working capital and other adjustments."
The company also has set up a $25 million back-up line of credit for working capital and for future growth initiatives.
Symyx struck the agreement to buy MDL in August, when it said it expected combined software and database operations to be around $100 million in 2008. At the time of the agreement, Symyx said MDL had around 1,000 customers and around 50,000 content and software users. 
Symyx said this week that it expects to incur “significant restructuring and one-time acquisition costs" in the fourth quarter of 2007.

Japan’s National Cancer Research Institute
Uses Nonlinear Dynamics’ Progenesis Software
Nonlinear Dynamics, a proteomics software provider, said this week that the National Cancer Research Institute in Tokyo is successfully using the company’s Progenesis SameSpots as part of its biomarker discovery program.
The NCR Institute adopted this new technology to support its mission of advancing knowledge in cancer prevention, diagnosis and therapy for cancer control. Progenesis SameSpots analyzes 2D single stain and DIGE images in 2D-based proteomics research.

Organon Extends and Expands GeneGo's License
Organon has extended and expanded its license of GeneGo's software and database products, GeneGo said this week.
Organon extended its license of the MetaCore data analysis platform from a deal it originally signed with GeneGo in 2005.
Under the new agreement, the Dutch pharmaceuticals developer also added a new license for GeneGo's MetaLink software.
Financial terms of the agreements were not released.

Filed under

The Scan

Harvard Team Report One-Time Base Editing Treatment for Motor Neuron Disease in Mice

A base-editing approach restored SMN levels and improved motor function in a mouse model of spinal muscular atrophy, a new Science paper reports.

International Team Examines History of North American Horses

Genetic and other analyses presented in Science find that horses spread to the northern Rockies and Great Plains by the first half of the 17th century.

New Study Examines Genetic Dominance Within UK Biobank

Researchers analyze instances of genetic dominance within UK Biobank data, as they report in Science.

Cell Signaling Pathway Identified as Metastasis Suppressor

A new study in Nature homes in on the STING pathway as a suppressor of metastasis in a mouse model of lung cancer.