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SRS Evolution, GenomatixSuite, Merlin, SBW 1.0.1


Heidelberg, Germany-based Lion Bioscience has released SRS Evolution, a package of software tools based on the company’s SRS integration platform. SRS Evolution includes the latest version of SRS, SRS7, which now supports the Emboss suite of open source tools as well as XML integration. In addition, SRS Evolution offers several new features, including SRS 3D, a view of sequence, structure, and feature data based upon a pre-calculated database of sequence-to-structure alignments, and SRS Relational, which was developed in collaboration with Novartis Pharma to support relational database integration.


Genomatix of Munich, Germany, has released GenomatixSuite, a single interface for three programs, ElDorado, Chip2Promoter, and GEMS. The ElDorado portal integrates biomolecular data with literature analysis, Chip2Promoter retrieves and analyzes human promoters, and GEMS (Genome Exploring and Modeling Software) integrates a series of computational tasks to assess the functional structure of genomic sequences. The company is currently offering free one-month trials for academic and commercial users at

Ensembl 7.29.1, which contains the annotation for human build 29, is now available from the Sanger Institute and the European Bioinformatics Institute at www.ensembl. org/Homo_sapiens. It contains 22,808 confirmed gene predictions. A new data-mining interface called Ensembl Mart is also available at www., where users can apply filters to retrieve lists of biological objects from data in the Ensembl database.


The Center for Statistical Genetics at the University of Michigan has released version 0.9.2 of Merlin, a pedigree analysis software package, at merlin. Enhancements include support of covariates in variance components analyses and improved source code portability.


The Systems Biology Workbench Development Group at the California Institute of Technology has released SBW 1.0.1 at and The new version supports C, C++, Delphi, Java, Perl, and Python and runs on Linux and Windows 98, 2000, and XP. Mac OS X support is expected in the “near future,” according to the SBW developers.

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The Scan

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Arizona Bill Before Judge

The Arizona Daily Star reports that a judge weighing whether a new Arizona law restricting abortion due to genetic conditions is a ban or a restriction.

Additional Genes

Wales is rolling out new genetic testing service for cancer patients, according to BBC News.

Science Papers Examine State of Human Genomic Research, Single-Cell Protein Quantification

In Science this week: a number of editorials and policy reports discuss advances in human genomic research, and more.