OAKLAND, Calif.--Bristol-Myers Squibb has licensed from Pangea Systems here state-of-the-art computational tools that will allow faster and more accurate clustering and alignment of expressed sequence tags (EST's) and full-length sequences within large public and proprietary databases. Pangea said the tools will provide Squibb with accurate molecular information in order to increase the sensitivity with which molecular targets can be identified and the selectivity with which they can be validated for use in the drug discovery process.
"Some of the computational challenges of proteomics, expression profiling, and sequence datamining can be reasonably approached only if we can reduce the complexity and redundancy of large EST databases," commented Wes Cosand, Squibb's director of genomic technology. He called the Pangea tool "an excellent package for performing this task."