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Silicon Genetics, European Bioinformatics Institute and the Sanger Institute, GenBank, EMC


Silicon Genetics of Redwood City, Calif., has released MetaMine 1.0, an application that creates reports for researchers based on information extracted from gene expression data repositories.


The Ensembl team at the European Bioinformatics Institute and the Sanger Institute has released version 3 of the mouse draft genome assembly at Mus_musculus.

Ensembl’s automatic annotation of the genome predicted 22,444 genes. There are also links provided between the human and mouse genomes at the chromosome level, the gene level, and the DNA level.


GenBank release 129.0 is available via ftp from the National Center for Biotechnology Information at Release 129.0 contains 19,072,679,701 base pairs and 16,769,983 entries — up 1.98 billion base pairs and 1,304,658 sequence records from the February 128.0 release. The uncompressed flat files require approximately 66.43 GB for the sequence files only. The ASN.1 version requires around 57.43 GB.


Hopkinton, Mass.-based EMC has released Centera, a content-addressed storage solution that is optimized for fixed content. The company said that Centera’s ability to store unchanging objects such as electronic documents and digital images should be of interest to pharmaceutical and biotech companies who must retain fixed electronic records for FDA filing.

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The Scan

Researchers Compare WGS, Exome Sequencing-Based Mendelian Disease Diagnosis

Investigators find a diagnostic edge for whole-genome sequencing, while highlighting the cost advantages and improving diagnostic rate of exome sequencing in EJHG.

Researchers Retrace Key Mutations in Reassorted H1N1 Swine Flu Virus With Avian-Like Features

Mutations in the acidic polymerase-coding gene boost the pathogenicity and transmissibility of Eurasian avian-like H1N1 swine influenza viruses, a PNAS paper finds.

Genome Sequences Reveal Evolutionary History of South America's Canids

An analysis in PNAS of South American canid species' genomes offers a look at their evolutionary history, as well as their relationships and adaptations.

Lung Cancer Response to Checkpoint Inhibitors Reflected in Circulating Tumor DNA

In non-small cell lung cancer patients, researchers find in JCO Precision Oncology that survival benefits after immune checkpoint blockade coincide with a dip in ctDNA levels.