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Scripps-Led Network Launches Contest to Assess Computational Methods for GPCR Protein Modeling


Organizers of the G Protein-Coupled Receptors Network, a consortium led by the Scripps Research Institute that aims to determine the structure and function of GPCRs, have launched a competition that will assess computational methods for GPCR structure-based homology modeling and docking.

This year’s contest will run from Feb. 1 until March 3, the organizers said.

Participants are asked to submit up to five prediction models per target for four GPCR-ligand complexes, which haven’t been published. While submitting model predictions for all four targets is strongly encouraged, participants can choose to work on fewer targets, the organizers said.

Interested researchers should register here. Once the registration process is complete, organizers will send the receptor sequence and ligand information.

Now in its third round, the GPCR Dock assessment is intended to evaluate the current status and uncover new areas of needed development in GPCR computational biology, the organizers said.