Skip to main content
Premium Trial:

Request an Annual Quote

SBI, Quest Team to Apply Pharmacogenomics to Drug And Healthcare Research


SAN DIEGO--Quest Diagnostics of Teterboro, N.J., and Structural Bioinformatics here announced a strategic alliance regarding the application of structural pharmacogenomics to clinical testing and pharmaceutical research. Structural Bioinformatics will extend existing and generate new proprietary target-specific structural variant database modules for a number of therapeutic targets based on Quest's clinical sequence databases. These modules will permit modeling of structurally variant proteins to facilitate design and identification of best-in-class drug compounds, according to the two companies. The databases will be jointly offered under the QSVdBase name by both companies for licensing to the pharmaceutical industry within the year. Patrick Hess, director of biotechnology affairs at Quest's Nichols Institute, said, "The structural variant databases generated from our genotyping databases should provide a fertile new source of information helpful in the design of new antiviral compounds using the structure-based drug discovery approach pioneered by Structural Bioinformatics."

Filed under

The Scan

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.

Team Presents Cattle Genotype-Tissue Expression Atlas

Using RNA sequences representing thousands of cattle samples, researchers looked at relationships between cattle genotype and tissue expression in Nature Genetics.

Researchers Map Recombination in Khoe-San Population

With whole-genome sequences for dozens of individuals from the Nama population, researchers saw in Genome Biology fine-scale recombination patterns that clustered outside of other populations.

Myotonic Dystrophy Repeat Detected in Family Genome Sequencing Analysis

While sequencing individuals from a multi-generation family, researchers identified a myotonic dystrophy type 2-related short tandem repeat in the European Journal of Human Genetics.