Rutgers Statistical Method Assesses LOH in Tumor Suppressor Genes, Supplements Sequencing Panels

Jan 29, 2018

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NEW YORK (GenomeWeb) – Investigators at Rutgers Cancer Institute of New Jersey have developed a statistical method called the loss of heterozygosity-germline inference calculator (LOHGIC), which they claim is able to classify mutations in tumor suppressor genes as somatic or germline and predict gene loss in cancer cells using data from tumor-only deep-sequencing assays.

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