Skip to main content
Premium Trial:

Request an Annual Quote

Rothamsted Research Buys Second TimeLogic DeCypher System

Premium

Active Motif subsidiary TimeLogic said this week that the Rothamsted Research, a UK-based agricultural research institute, has purchased the latest version of its DeCypher system to enhance its high-throughput genome annotation efforts.

The new hardware adds to an existing DeCypher system at the institute and was purchased to help researchers manage “the increasing influx of next-generation sequence data and newly sequenced genomes from species relevant to our research in sustainable agriculture,” Christopher Rawlings, head of Rothamsted’s department of computational and systems biology, said in a statement.

TimeLogic’s DeCypher systems combine custom field programmable gate array circuitry with optimized implementations of Blast, Smith-Waterman, hidden Markov model, and gene modeling algorithms.

Jan Taubert, a senior bioinformatician in Rothamsted’s department of computational and systems biology, said researchers will use the hardware to analyze sequence data from the wheat genome and studies of the microbial biodiversity of soils as well as to compare crop pathogen genomes.

The Scan

Octopus Brain Complexity Linked to MicroRNA Expansions

Investigators saw microRNA gene expansions coinciding with complex brains when they analyzed certain cephalopod transcriptomes, as they report in Science Advances.

Study Tracks Outcomes in Children Born to Zika Virus-Infected Mothers

By following pregnancy outcomes for women with RT-PCR-confirmed Zika virus infections, researchers saw in Lancet Regional Health congenital abnormalities in roughly one-third of live-born children.

Team Presents Benchmark Study of RNA Classification Tools

With more than 135 transcriptomic datasets, researchers tested two dozen coding and non-coding RNA classification tools, establishing a set of potentially misclassified transcripts, as they report in Nucleic Acids Research.

Breast Cancer Risk Related to Pathogenic BRCA1 Mutation May Be Modified by Repeats

Several variable number tandem repeats appear to impact breast cancer risk and age at diagnosis in almost 350 individuals carrying a risky Ashkenazi Jewish BRCA1 founder mutation.