US Patent 7,139,665. Computational method for designing enzymes for incorporation of non natural amino acids into proteins. Inventors: Deepshikha Datta, Pin Wang, Isaac Carrico, Stephen Mayo, David Tirrell. Assignee: California Institute of Technology.
Protects methods, reagents, and computational tools for designing non-natural substrate analogs for enzymes, especially for designing unnatural amino acid analogs for aminoacyl tRNA synthetases, such as the Phe tRNA synthetase.


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The New York Times and ProPublica say that many physicians fail to disclose their financial ties when publishing in medical journals.

The Wall Street Journal reports Human Longevity's valuation has dropped by 80 percent.

Science reports that the US National Cancer Institute is cutting its operating budget by 5 percent.

In PLOS this week: similar variants seen in bullbogs, people with Robinow syndrome; ApoE genotypes in African-American, Puerto Rican populations; and more.