Recent Patents in Bioinformatics, Feb.— March 2007 | GenomeWeb
US Patent 7,200,531. Conformation-activity relationship of apoptosis-inducing phosphodiester oligonucleotides. Inventors: Nigel Phillips, Mario Filion, Zdenek Richard Holan, Assignee: Bionicrie Life Sciences.
Protects a computer-based method for evaluating oligonucleotides for biological activity based on the three-dimensional structure and charge characteristics. Biological activities include, but are not limited to, cellular proliferation, induction of cell cycle arrest, and apoptosis.


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