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PubMed Search by Protein Name, Proteome BioKnowledge Library, MATLAB , BioCyc, Pfam 11.0, Bioconductor 1.3, CellDesigner 1.1

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Ariadne Genomics has released a free web service — PubMed Search by Protein Name — at http://www.ariadnegenomics.com/products . The text-mining service is designed to retrieve abstracts containing all aliases for proteins of interest, while avoiding casual keyword matches, according to the company. The underlying technology for the service is Ariadne’s MedScan text-mining tool.

Incyte is offering free access to Alzheimer disease-related data in its Proteome BioKnowledge Library during November as part of its monthly Disease Spotlight program. The Alzheimer Disease Spotlight provides 25 protein reports related to Alzheimer disease with curated annotations based on relevant publications. The data is available at www.incyte.com/diseaseview

The MathWorks has released a Bioinformatics Toolbox for MATLAB — an addition to the data analysis and algorithm development environment that provides access to standard genomic file formats, Web-based databases such as GenBank and PIR, and online data sources. The toolbox also offers specialized routines for visualizing microarray data. The Bioinformatics Toolbox is available immediately for Windows, UNIX/Linux, and Macintosh systems. Pricing starts at $1,000.

Version 7.6 of BioCyc is now available at http://biocyc.org/. Highlights include two new pathway/genome databases: E. coli O157:H7 and Shigella flexneri 2457T. In addition, the HumanCyc database is now available as an open database for downloading as a set of flat files at http://biocyc.org/download.shtml.

Pfam 11.0 is now available from the Pfam consortium at http://www.sanger.ac.uk/Software/Pfam and other sites. The collection of protein domain family alignments constructed using profile hidden Markov models now contains 7,255 families.

Bioconductor 1.3, which is intended to be operated with R version 1.8.X, is available at http://www.bioconductor.org/. New features include several improvements to the Affy package, improved graph/network handling, and an interface to the curated SNPper data resource maintained at Children’s Hospital Boston.

CellDesigner 1.1, a modeling tool for biochemical networks with a graphical user interface, is available from the Systems Biology Institute at http://www.systems-biology.org/002/001.html. Features include read/write models in SBML Level 1 format, drawing state transition diagrams of proteins, and simulations using the Systems Biology Workbench simulator modules.

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The Scan

Support for Moderna Booster

An FDA advisory committee supports authorizing a booster for Moderna's SARS-CoV-2 vaccine, CNN reports.

Testing at UK Lab Suspended

SARS-CoV-2 testing at a UK lab has been suspended following a number of false negative results.

J&J CSO to Step Down

The Wall Street Journal reports that Paul Stoffels will be stepping down as chief scientific officer at Johnson & Johnson by the end of the year.

Science Papers Present Proteo-Genomic Map of Human Health, Brain Tumor Target, Tool to Infer CNVs

In Science this week: gene-protein-disease map, epigenomic and transcriptomic approach highlights potential therapeutic target for gliomas, and more