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Proteome BioKnowledge Library, Genome Browser, Ensembl 10, Proteomweaver 2.0


Incyte Genomics has released an enhanced version of its Proteome BioKnowledge Library that includes a Disease Curation Module, which categorizes proteins by disease type. The module contains manually curated data on protein function and disease roles, which is arranged into four categories: Therapeutic Target, Molecular Mechanism, Diagnostic Marker, and Negative Correlation. The module currently includes information from 5,415 articles representing 263 journals and shows relationships between 873 diseases and 1,026 proteins. Incyte said it updates the information weekly.

Version 17 of the University of California, Santa Cruz, Genome Browser is now available at New features include support for intersections of tracks, a new summary statistics output format, and the ability to output query results as a custom annotation track that can be viewed in the Genome Browser. In addition, two new display modes — pack and squish — allow users to view more than one annotation track feature on the same line. Users can also save annotation track images in postscript or PDF format. New annotation tracks include a known genes track, a superfamily track, and additional annotation tracks on the latest human and rat assemblies.

Ensembl 10 — a coordinated release of new data and updated schema for nine genomes — is now available at The release includes new assembly and gene build data for Fugu rubripes, Anopheles gambiae, and Caenorhabditis briggsae. Links to Affymetrix and Sanger Institute microarray chips on a per-transcript basis are also available, and are linked to a new pathway-level database, Genome-KnowledgeBase.

Definiens has released Proteomweaver 2.0 for automated analysis of 2D protein gels. Two versions of the software are available: the Professional Edition permits up to 20 gels to be analyzed simultaneously, while the Enterprise Edition can process up to 500 gels in a single experiment.


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The Scan

Alzheimer's Risk Gene Among Women

CNN reports that researchers have found that variants in MGMT contribute to Alzheimer's disease risk among women but not men.

Still Hanging Around

The Guardian writes that persistent pockets of SARS-CoV-2 in the body could contribute to long COVID.

Through a Little Spit

Enteric viruses like norovirus may also be transmitted through saliva, not just the fecal-oral route, according to New Scientist.

Nature Papers Present Method to Detect Full Transcriptome, Viruses Infecting Asgard Archaea, More

In Nature this week: VASA-seq approach to detect full transcriptome, analysis of viruses infecting Asgard archaea, and more.