Skip to main content
Premium Trial:

Request an Annual Quote

Protein Pathways Gets $100,000 SBIR Grant



OS ANGELES--Protein Pathways received a $100,000 SBIR phase I grant from the US National Institutes of Health to assign functions, using computational methods, to more than 1,500 genes from the Mycobacterium tuberculosis genome. Of the nearly 4,000 genes in the completely sequenced TB genome, greater than 40 percent have no associated functional information or sequence homology to proteins of known function. The company's functional analyses will identify genes essential for viability or virulence as antibiotic targets. The methods will provide rational targets in new antibiotic classes, as well as supplement currently targeted pathways. Information contained in fully sequenced prokaryotic and eukaryotic genomes offers the opportunity to develop novel anti-infective agents.

Filed under

The Scan

White-Tailed Deer Harbor SARS-CoV-2 Variants No Longer Infecting Humans, Study Finds

A new study in PNAS has found that white-tailed deer could act as a reservoir of SARS-CoV-2 variants no longer found among humans.

Study Points to Benefits of Local Consolidative Therapy, Targeted Treatments in Cancer Care

In JCO Precision Oncology, researchers report that local consolidative therapy combined with molecularly targeted treatments could improve survival for some lung cancer patients.

Genetic Variants That Lower LDL Cholesterol Linked to Reduced Heart Disease Risk

Rare variants in two genes that lower LDL cholesterol are also associated with a decreased risk of coronary heart disease, according to a new JAMA Cardiology study.

Study Links Evolution of Longevity, Social Organization in Mammals

With the help of comparative phylogenetics and transcriptomics, researchers in Nature Communications see ties between lifespan and social organization in mammals.