In Print: Bioinformatics Tool-Related Papers of Note, December 2005 | GenomeWeb

Alter O, Golub GH. Reconstructing the pathways of a cellular system from genome-scale signals by using matrix and tensor computations. [Proc Natl Acad Sci USA. 2005 Dec 6;102(49):17559-64]: Describes the use of the matrix eigenvalue decomposition (EVD) and pseudoinverse projection and a tensor higher-order EVD (HOEVD) in reconstructing the pathways that compose a cellular system from genome-scale nondirectional networks of correlations among the genes of the system. The authors illustrate the method using yeast DNA microarray data.

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