In Print: Bioinformatics Tool-Related Papers of Note, Dec. 2004 | GenomeWeb

Blanchette M, Green E, Miller W, Haussler D. Reconstructing large regions of an ancestral mammalian genome in silico. [Genome Research 14:2412-2423, 2004]: Describes the computational reconstruction of an ancient genome sequence around the CFTR locus using genomic sequences from 19 extant mammals. Detailed examination suggests the reconstruction is accurate and that it allows researchers to identify features in modern species, such as remnants of ancient transposon insertions, that were not identified by direct analysis.

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