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Premier Biosoft, SGI, Ensembl 41, and National Center for Biotechnology Information

Premier Biosoft has released SimGlycan, a glycan mass fingerprinting tool that predicts glycan structure by matching an experimental mass spec profile with its own database. The software generates a list of all probable glycans that are close to the experimental data.

SGI has launched the SGI Scientific Workflow Solution, an integrated set of hardware and software tailored to scientific computing. The system offers a common Linux operating system across all platforms and a single job-scheduler. It includes the company’s Altix XE cluster line and RASC (Reconfigurable Application-Specific Computing) technology. SGI said the Scientific Workflow Solution will be offered in several versions optimized for major fields of study, including bioscience, and that it will announce “specific configurations, pricing, and availability” in the coming months.

Ensembl 41 is available at Features include the new assembly of the chimp genome, a new genebuild for zebrafish, an import of Wormbase 160, and new functional genomics databases for mouse and human.


The National Center for Biotechnology Information has released GenBank 156.0 here. The release contains 66,925,938,907 base pairs and 62,765,195 entries. Uncompressed, the 156.0 flat files require about 235 GB for the sequence files only. The ASN.1 version requires around 204 GB.

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The Scan

Genome Sequences Reveal Range Mutations in Induced Pluripotent Stem Cells

Researchers in Nature Genetics detect somatic mutation variation across iPSCs generated from blood or skin fibroblast cell sources, along with selection for BCOR gene mutations.

Researchers Reprogram Plant Roots With Synthetic Genetic Circuit Strategy

Root gene expression was altered with the help of genetic circuits built around a series of synthetic transcriptional regulators in the Nicotiana benthamiana plant in a Science paper.

Infectious Disease Tracking Study Compares Genome Sequencing Approaches

Researchers in BMC Genomics see advantages for capture-based Illumina sequencing and amplicon-based sequencing on the Nanopore instrument, depending on the situation or samples available.

LINE-1 Linked to Premature Aging Conditions

Researchers report in Science Translational Medicine that the accumulation of LINE-1 RNA contributes to premature aging conditions and that symptoms can be improved by targeting them.